Research workbench
Structure of human inositol 1,3,4-trisphosphate 5/6-kinase
Analyse Structure of human inositol 1,3,4-trisphosphate 5/6-kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ODT
- Type
- protein
- Length
- 315 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inositol-tetrakisphosphate 1-kinase
- EC
- 2.7.1.134, 2.7.1.159
- UniProt
- Q13572
- Pockets
- 2 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134, 2.7.1.159) | protein | 315 | 37% helix, 23% strand | Q13572 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 365 | 0.73 | 0.85 | 52 | empty |
| 2 | 69 | 0.29 | 0.73 | 19 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 2ODT · Structure of human Inositol 1,3,4-trisphosphate 5/6-kinase · the same entry in another collection · chain X against X, TM-score 1.00
- Q13572 · AlphaFold monomer V2.0 prediction for inositol-tetrakisphosphate 1-kinase (Q13572) · a predicted model of the same protein · chain X against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13572
- Elsewhere: RCSB PDB 2ODT · PDBe 2ODT · UniProt Q13572
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