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Stefin B (cystatin B) tetramer

Analyse Stefin B (cystatin B) tetramer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OCT
Type: protein
Length: 192 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cystatin B
UniProt: P04080
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 2 distinct chains · 19% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cystatin B	protein	97	19% helix, 42% strand	P04080
B	Cystatin B	protein	95	19% helix, 46% strand	P04080

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	207	0.48	0.75	30	empty

Interfaces

1 interface between chains.

A–B · 2197 Å² buried · 29 hydrogen bonds · protein-protein

Compared structures

2OCT · Stefin B (Cystatin B) tetramer · the same entry in another collection · chain A against A, TM-score 1.00
P04080 · AlphaFold monomer V2.0 prediction for cystatin-B (P04080) · a predicted model of the same protein · chain B against A, TM-score 0.48

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04080
Elsewhere: RCSB PDB 2OCT · PDBe 2OCT · UniProt P04080

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