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Solution NMR structure: northeast structural genomics consortium target SIR5

Analyse Solution NMR structure: northeast structural genomics consortium target SIR5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2OA4
Type
protein
Length
101 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
SIR5
UniProt
Q5LST8
Pockets
2 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 41% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASIR5protein10141% helix, 6% strandQ5LST8

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1700.400.7913empty
2570.300.7512empty

Compared structures

  • 2OA4 · Solution NMR Structure: Northeast Structural Genomics Consortium Target SiR5 · the same entry in another collection · chain A against A, TM-score 1.00

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