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Crystal structure of the pribnow box recognition region of sigc from mycobacterium tuberculosis

Analyse Crystal structure of the pribnow box recognition region of sigc from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2O7G
Type: protein
Length: 177 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable RNA polymerase sigma-C factor
UniProt: P66809
Ligands: SO4
Pockets: 1 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable RNA polymerase sigma-C factor	protein	88	84% helix, 0% strand	P66809
B	Probable RNA polymerase sigma-C factor	protein	89	76% helix, 0% strand	P66809

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.64	0.86	20	SO4

Interfaces

1 interface between chains.

A–B · 727 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

2O7G · Crystal structure of the Pribnow Box recognition region of SigC from Mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P66809
Elsewhere: RCSB PDB 2O7G · PDBe 2O7G · UniProt P66809

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