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Solution structure of the first SH3 domain of human vinexin and its interaction with the peptides from vinculin

Analyse Solution structure of the first SH3 domain of human vinexin and its interaction… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NWM
Type: protein
Length: 59 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vinexin
UniProt: O60504
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 5% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vinexin	protein	59	5% helix, 44% strand	O60504

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.33	0.77	14	empty

Compared structures

2NWM · Solution structure of the first SH3 domain of human Vinexin and its interaction with the… · the same entry in another collection · chain A against A, TM-score 1.00
O60504 · AlphaFold monomer V2.0 prediction for vinexin (O60504) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60504
Elsewhere: RCSB PDB 2NWM · PDBe 2NWM · UniProt O60504

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