Research workbench

Crystal structure of sek

Analyse Crystal structure of sek in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NTT
Type: protein
Length: 434 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Staphylococcal enterotoxin K
UniProt: Q5HHK0
Ligands: CL
Pockets: 5 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Staphylococcal enterotoxin K	protein	217	21% helix, 38% strand	Q5HHK0

Ligands and binding sites

CL · Chloride ion · ion · 13 copies · chains A, B
EDO · 1,2-ethanediol · additive · 10 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.45	0.82	14	CL
2	110	0.42	0.77	22	empty
3	58	0.35	0.78	14	CL
4	90	0.32	0.73	20	CL
5	54	0.31	0.76	22	EDO

Interfaces

1 interface between chains.

A–B · 563 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

2NTT · Crystal Structure of SEK · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5HHK0
Elsewhere: RCSB PDB 2NTT · PDBe 2NTT · UniProt Q5HHK0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.