Research workbench
Crystal structure of FMN-bound protein MM1853 from methanosarcina mazei, pfam DUF447
Analyse Crystal structure of FMN-bound protein MM1853 from methanosarcina mazei, pfam… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2NR4
- Type
- protein
- Length
- 373 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein
- UniProt
- Q8PVV4
- Ligands
- FMN
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Conserved hypothetical protein | protein | 191 | 40% helix, 32% strand | Q8PVV4 |
| B | Conserved hypothetical protein | protein | 182 | 38% helix, 35% strand | Q8PVV4 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 505 | 0.75 | 0.83 | 51 | empty |
| 2 | 338 | 0.65 | 0.80 | 31 | FMN |
| 3 | 429 | 0.62 | 0.77 | 38 | FMN |
| 4 | 74 | 0.29 | 0.72 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1662 Ų buried · 32 hydrogen bonds · protein-protein
Compared structures
- 2NR4 · Crystal structure of FMN-bound protein MM1853 from Methanosarcina mazei, Pfam DUF447 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8PVV4
- Elsewhere: RCSB PDB 2NR4 · PDBe 2NR4 · UniProt Q8PVV4
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