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Moea D59N mutant

Analyse Moea D59N mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NQK
Type: protein
Length: 806 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Molybdopterin biosynthesis protein moea
UniProt: P12281
Pockets: 8 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 22% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Molybdopterin biosynthesis protein moea	protein	403	22% helix, 33% strand	P12281

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	843	0.78	0.81	94	empty
2	878	0.75	0.79	74	empty
3	664	0.69	0.77	58	empty
4	183	0.55	0.79	21	empty
5	118	0.47	0.79	18	empty

Interfaces

1 interface between chains.

A–B · 2245 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

2NQK · MoeA D59N mutant · the same entry in another collection · chain A against A, TM-score 1.00
P12281 · AlphaFold monomer V2.0 prediction for molybdopterin molybdenumtransferase (P12281) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P12281
Elsewhere: RCSB PDB 2NQK · PDBe 2NQK · UniProt P12281

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