Research workbench
NMR solution structure of MAL/TIRAP tir domain (C116A)
Analyse NMR solution structure of MAL/TIRAP tir domain (C116A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2NDH
- Type
- protein
- Length
- 143 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- TOLL/INTERLEUKIN-1 receptor domain-containing adapter protein
- UniProt
- P58753
- Pockets
- 4 · best druggability 0.64
Structure
solution nmr · 1 distinct chain · 34% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | TOLL/INTERLEUKIN-1 receptor domain-containing adapter protein | protein | 143 | 34% helix, 8% strand | P58753 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.64 | 0.92 | 19 | empty |
| 2 | 393 | 0.62 | 0.77 | 49 | empty |
| 3 | 153 | 0.49 | 0.77 | 24 | empty |
| 4 | 85 | 0.44 | 0.80 | 19 | empty |
Compared structures
- 2NDH · NMR solution structure of MAL/TIRAP TIR domain (C116A) · the same entry in another collection · chain A against A, TM-score 1.00
- P58753 · AlphaFold monomer V2.0 prediction for TOLL/INTERLEUKIN-1 receptor domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58753
- Elsewhere: RCSB PDB 2NDH · PDBe 2NDH · UniProt P58753
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