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Structural insight for dynamics of R(CGG) motif RNA found in fragile X syndrome/ fragile X tremor ataxia at 25 degree C

Analyse Structural insight for dynamics of R(CGG) motif RNA found in fragile X… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NCR
Type: RNA
Length: 18 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA_(5'-R(P*CP*CP*GP*CP*GP*GP*CP*GP*G)-3')
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
S, A	RNA_(5'-R(PCPCPGPCPGPGPCPGP*G)-3')	rna	9	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.32	0.73	13	empty

Interfaces

1 interface between chains.

S–A · 468 Å² buried · 41 hydrogen bonds · nucleic-nucleic

Compared structures

2NCR · Structural insight for dynamics of r(CGG) motif RNA found in Fragile X syndrome/ Fragile… · the same entry in another collection · chain S against S, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2NCR · PDBe 2NCR

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