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P75NTR DD:RIP2 card

Analyse P75NTR DD:RIP2 card in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N83
Type: protein
Length: 199 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tumor necrosis factor receptor superfamily member 16; Receptor-interacting…
EC: 2.7.11.1, 2.7.10.2
UniProt: P08138, O43353

Structure

solution nmr · 2 distinct chains · 63% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tumor necrosis factor receptor superfamily member 16	protein	94	67% helix, 2% strand	P08138
B	Receptor-interacting SERINE/THREONINE-protein kinase 2 (EC 2.7.11.1, 2.7.10.2)	protein	105	59% helix, 0% strand	O43353

Interfaces

1 interface between chains.

A–B · 1477 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

2N83 · p75NTR DD:RIP2 CARD · the same entry in another collection · chain A against A, TM-score 1.00
P08138 · AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member… · a predicted model of the same protein · chain A against A, TM-score 0.77
O43353 · AlphaFold monomer V2.0 prediction for receptor-interacting SERINE/THREONINE-protein… · a predicted model of the same protein · chain B against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08138
Every structure of UniProt O43353
Elsewhere: RCSB PDB 2N83 · PDBe 2N83 · UniProt P08138 · UniProt O43353

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