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NMR structure of kora, a plasmid-encoded, global transcription regulator kora

Analyse NMR structure of kora, a plasmid-encoded, global transcription regulator kora in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N5G
Type: protein
Length: 202 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trfb transcriptional repressor protein
UniProt: P03052
Pockets: 1 · best druggability 0.54

Structure

solution nmr · 1 distinct chain · 61% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Trfb transcriptional repressor protein	protein	101	61% helix, 5% strand	P03052

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.54	0.86	16	empty

Interfaces

1 interface between chains.

A–B · 927 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

2N5G · NMR structure of KorA, a plasmid-encoded, global transcription regulator KorA · the same entry in another collection · chain A against A, TM-score 1.00
P03052 · AlphaFold monomer V2.0 prediction for trfb transcriptional repressor protein (P03052) · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03052
Elsewhere: RCSB PDB 2N5G · PDBe 2N5G · UniProt P03052

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