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Solution structure of the HIV-1 intron splicing silencer and its interactions with the UP1 domain of hnrnp A1

Analyse Solution structure of the HIV-1 intron splicing silencer and its interactions… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N4L
Type: RNA
Length: 53 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (53-mer)
Pockets: 1 · best druggability 0.25

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (53-mer)	rna	53	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	70	0.25	0.71	13	empty

Compared structures

2N4L · Solution Structure of the HIV-1 Intron Splicing Silencer and its Interactions with the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2N4L · PDBe 2N4L

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