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Solution structure of the link module of human tsg-6 in presence of a chondroitin 4-sulfate hexasaccharide

Analyse Solution structure of the link module of human tsg-6 in presence of a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2N40
Type: protein
Length: 98 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tumor necrosis factor-inducible gene 6 protein
UniProt: P98066
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 15% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tumor necrosis factor-inducible gene 6 protein	protein	98	15% helix, 13% strand	P98066

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.30	0.76	15	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2N40 · Solution structure of the link module of human tsg-6 in presence of a chondroitin… · the same entry in another collection · chain A against A, TM-score 1.00
P98066 · AlphaFold monomer V2.0 prediction for tumor necrosis factor-inducible gene 6 protein… · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P98066
Elsewhere: RCSB PDB 2N40 · PDBe 2N40 · UniProt P98066

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