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G-quadruplex structure of an anti-proliferative DNA sequence

Analyse G-quadruplex structure of an anti-proliferative DNA sequence in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2N3M
Type
DNA
Length
28 nucleotides
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA_(28-mer)
Pockets
1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA_(28-mer)dna28——

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1540.310.779empty

Compared structures

  • 2N3M · G-quadruplex structure of an anti-proliferative DNA sequence · the same entry in another collection · chain A against A, TM-score 1.00

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