Research workbench
Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G G X O tetrad
Analyse Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G G X O tetrad in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2MWZ
- Type
- DNA
- Length
- 24 nucleotides
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*(8OG) P*GP*GP*TP*TP*AP*GP*GP*(3ZO)P*TP*TP*AP*GP*GP*GP*A…
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*(8OG) P*GP*GP*TP*TP*AP*GP*GP*(3ZO)P*TP*TP*AP*GP*GP*GP*A)-3') | dna | 24 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.36 | 0.81 | 9 | empty |
Modifications
Observed in the structure: 2 modified (nucleotide modification).
Compared structures
- 2MWZ · Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G G X O tetrad · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2MWZ · PDBe 2MWZ
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