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Solution structure of hox homeodomain

Analyse Solution structure of hox homeodomain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2MSY
Type
protein
Length
68 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Homeobox protein hox-C9
UniProt
P31274
Pockets
1 · best druggability 0.28

Structure

solution nmr · 1 distinct chain · 56% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHomeobox protein hox-C9protein6856% helix, 0% strandP31274

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1550.280.7313empty

Compared structures

  • 2MSY · Solution structure of Hox homeodomain · the same entry in another collection · chain A against A, TM-score 1.00
  • P31274 · AlphaFold monomer V2.0 prediction for homeobox protein hox-C9 (P31274) · a predicted model of the same protein · chain A against A, TM-score 0.56

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