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Solution NMR structure of TRNAPRO:MLV nucleocapsid protein (1:1) complex

Analyse Solution NMR structure of TRNAPRO:MLV nucleocapsid protein (1:1) complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2MS1
Type: protein + RNA
Length: 126 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleocapsid protein P10; Trnapro
UniProt: P03355
Ligands: ZN
Pockets: 4 · best druggability 0.58

Structure

solution nmr · 2 distinct chains · 5% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleocapsid protein P10	protein	55	5% helix, 4% strand	P03355
B	Trnapro	rna	71	—	—

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	407	0.58	0.76	26	empty
2	267	0.54	0.77	22	empty
3	169	0.44	0.75	19	empty
4	81	0.31	0.74	11	empty

Interfaces

1 interface between chains.

A–B · 661 Å² buried · 18 hydrogen bonds · protein-nucleic

Compared structures

2MS1 · Solution NMR structure of tRNApro:MLV Nucleocapsid Protein (1:1) Complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03355
Elsewhere: RCSB PDB 2MS1 · PDBe 2MS1 · UniProt P03355

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