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AG(7-DEAZA)G fapy modified duplex

Analyse AG(7-DEAZA)G fapy modified duplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2MMS
Type
DNA
Length
20 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA_(5'-D(*CP*TP*AP*AP*(FAG)P*(7GU)P*TP*TP*CP*A)-3')…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA_(5'-D(*CP*TP*AP*AP*(FAG)P*(7GU)P*TP*TP*CP*A)-3')dna10——
BDNA_(5'-D(*TP*GP*AP*AP*CP*CP*TP*TP*AP*G)-3')dna10——

Interfaces

1 interface between chains.

  • A–B · 529 Ų buried · 37 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 2 modified (nucleotide modification).

Compared structures

  • 2MMS · AG(7-deaza)G FAPY modified duplex · the same entry in another collection · chain A against A, TM-score 1.00

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