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A tetrahelical DNA fold adopted by alternating ggg and gcg tracts

Analyse A tetrahelical DNA fold adopted by alternating ggg and gcg tracts in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2MJJ
Type
DNA
Length
30 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-D(*GP*GP*GP*AP*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*G)-3'
Pockets
1 · best druggability 0.59

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B5'-D(*GP*GP*GP*AP*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*G)-3'dna15——

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14040.590.7629empty

Interfaces

1 interface between chains.

  • A–B · 807 Ų buried · 65 hydrogen bonds · nucleic-nucleic

Compared structures

  • 2MJJ · A tetrahelical DNA fold adopted by alternating GGG and GCG tracts · the same entry in another collection · chain A against A, TM-score 1.00

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