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NMR structure of the chicken CD3 epsilon DELTA/GAMMA heterodimer

Analyse NMR structure of the chicken CD3 epsilon DELTA/GAMMA heterodimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2MIM
Type
protein
Length
178 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
CD3 epsilon PROTEIN,CD3 glycoprotein
UniProt
P70069, Q90768
Pockets
5 · best druggability 0.59

Structure

solution nmr · 1 distinct chain · 2% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACD3 epsilon PROTEIN,CD3 glycoproteinprotein1782% helix, 26% strandP70069, Q90768

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11410.590.8322empty
2500.470.8518empty
3580.460.8415empty
4980.380.7619empty
5680.290.7417empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 2MIM · NMR structure of the chicken CD3 epsilon delta/gamma heterodimer · the same entry in another collection · chain A against A, TM-score 1.00

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