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Structural and biophysical characterization of the mRNA interferase samazf from staphylococcus aureus.

Analyse Structural and biophysical characterization of the mRNA interferase samazf from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2MF2
Type: protein
Length: 264 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MRNA interferase mazf
EC: 3.1.-.-
UniProt: Q7A0D7
Pockets: 3 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 17% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	MRNA interferase mazf (EC 3.1.-.-)	protein	132	17% helix, 33% strand	Q7A0D7

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.37	0.75	26	empty
2	54	0.36	0.79	21	empty
3	91	0.35	0.75	25	empty

Interfaces

1 interface between chains.

A–B · 1398 Å² buried · 27 hydrogen bonds · protein-protein

Compared structures

2MF2 · Structural and biophysical characterization of the mRNA interferase SaMazF from… · the same entry in another collection · chain A against A, TM-score 1.00
Q7A0D7 · AlphaFold monomer V2.0 prediction for endoribonuclease mazf (Q7A0D7) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7A0D7
Elsewhere: RCSB PDB 2MF2 · PDBe 2MF2 · UniProt Q7A0D7

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