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Structural basis of the non-coding RNA rsmz acting as protein sponge: conformer R of RSMZ(1-72)/RSME(DIMER) 1TO3 complex

Analyse Structural basis of the non-coding RNA rsmz acting as protein sponge: conformer… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2MF1
Type
protein + RNA
Length
426 residues
Chains
7
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Carbon storage regulator homolog; RNA_(72-mer)
UniProt
Q4KEY0
Pockets
1 · best druggability 0.60

Structure

solution nmr · 2 distinct chains · 12% helix, 49% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D, E, FCarbon storage regulator homologprotein5912% helix, 49% strandQ4KEY0
GRNA_(72-mer)rna72——

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15710.600.7446empty

Interfaces

9 interfaces between chains.

  • C–D · 1974 Ų buried · 34 hydrogen bonds · protein-protein
  • E–F · 1959 Ų buried · 41 hydrogen bonds · protein-protein
  • A–B · 1919 Ų buried · 34 hydrogen bonds · protein-protein
  • B–G · 1300 Ų buried · 39 hydrogen bonds · protein-nucleic
  • D–G · 1226 Ų buried · 41 hydrogen bonds · protein-nucleic

Compared structures

  • 2MF1 · Structural basis of the non-coding RNA RsmZ acting as protein sponge: Conformer R of… · the same entry in another collection · chain A against A, TM-score 1.00

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