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Solution NMR structure of transcription factor gata-4 from homo sapiens, northeast structural genomics consortium (nesg) target HR4783B

Analyse Solution NMR structure of transcription factor gata-4 from homo sapiens… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M9W
Type: protein
Length: 63 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription factor gata-4
UniProt: P43694
Ligands: ZN
Pockets: 1 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 14% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription factor gata-4	protein	63	14% helix, 10% strand	P43694

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.38	0.74	19	empty

Compared structures

2M9W · Solution NMR Structure of Transcription Factor GATA-4 from Homo sapiens, Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
P43694 · AlphaFold monomer V2.0 prediction for transcription factor gata-4 (P43694) · a predicted model of the same protein · chain A against A, TM-score 0.59

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43694
Elsewhere: RCSB PDB 2M9W · PDBe 2M9W · UniProt P43694

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