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Solution structure of yeast dithiol glutaredoxin GRX8

Analyse Solution structure of yeast dithiol glutaredoxin GRX8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M80
Type: protein
Length: 109 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutaredoxin-8
UniProt: Q05926
Pockets: 2 · best druggability 0.70

Structure

solution nmr · 1 distinct chain · 49% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutaredoxin-8	protein	109	49% helix, 15% strand	Q05926

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.70	0.94	26	empty
2	123	0.59	0.84	15	empty

Compared structures

2M80 · Solution structure of yeast dithiol glutaredoxin Grx8 · the same entry in another collection · chain A against A, TM-score 1.00
Q05926 · AlphaFold monomer V2.0 prediction for glutaredoxin-8 (Q05926) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05926
Elsewhere: RCSB PDB 2M80 · PDBe 2M80 · UniProt Q05926

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