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Solution structure of human S100 calcium-binding protein A11

Analyse Solution structure of human S100 calcium-binding protein A11 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LUC
Type: protein
Length: 210 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein S100-A11
UniProt: P31949
Pockets: 2 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 64% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein S100-A11	protein	105	64% helix, 4% strand	P31949

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.34	0.77	13	empty
2	61	0.33	0.76	12	empty

Interfaces

1 interface between chains.

A–B · 1867 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

2LUC · Solution Structure of human S100 calcium-binding protein A11 · the same entry in another collection · chain A against A, TM-score 1.00
P31949 · AlphaFold monomer V2.0 prediction for protein S100-A11 (P31949) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31949
Elsewhere: RCSB PDB 2LUC · PDBe 2LUC · UniProt P31949

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