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Solution structure of phosphorylated crkl

Analyse Solution structure of phosphorylated crkl in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LQW
Type: protein
Length: 303 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Crk-like protein
UniProt: P46109
Pockets: 5 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 11% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Crk-like protein	protein	303	11% helix, 29% strand	P46109

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	139	0.46	0.77	24	empty
2	52	0.41	0.82	17	empty
3	117	0.38	0.74	23	empty
4	105	0.35	0.74	16	empty
5	58	0.33	0.77	18	empty

Modifications

Observed in the structure: 1 modified (phosphorylation).

Compared structures

2LQW · Solution structure of phosphorylated CRKL · the same entry in another collection · chain A against A, TM-score 1.00
P46109 · AlphaFold monomer V2.0 prediction for crk-like protein (P46109) · a predicted model of the same protein · chain A against A, TM-score 0.35

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46109
Elsewhere: RCSB PDB 2LQW · PDBe 2LQW · UniProt P46109

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