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Backbone structure of human membrane protein TMEM14A from noe data

Analyse Backbone structure of human membrane protein TMEM14A from noe data in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2LOO
Type
protein
Length
99 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Transmembrane protein 14A
UniProt
Q9Y6G1
Pockets
1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 61% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATransmembrane protein 14Aprotein9961% helix, 0% strandQ9Y6G1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11210.400.7521empty

Compared structures

  • 2LOO · Backbone structure of human membrane protein TMEM14A from NOE data · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y6G1 · AlphaFold monomer V2.0 prediction for transmembrane protein 14A (Q9Y6G1) · a predicted model of the same protein · chain A against A, TM-score 0.36

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