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Solution structure of E60A mutant AGR2

Analyse Solution structure of E60A mutant AGR2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LNT
Type: protein
Length: 140 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Anterior gradient protein 2 homolog
UniProt: O95994
Pockets: 3 · best druggability 0.54

Structure

solution nmr · 1 distinct chain · 29% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Anterior gradient protein 2 homolog	protein	140	29% helix, 8% strand	O95994

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.54	0.81	21	empty
2	94	0.38	0.76	23	empty
3	50	0.34	0.79	17	empty

Compared structures

2LNT · Solution structure of E60A mutant AGR2 · the same entry in another collection · chain A against A, TM-score 1.00
O95994 · AlphaFold monomer V2.0 prediction for anterior gradient protein 2 homolog (O95994) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95994
Elsewhere: RCSB PDB 2LNT · PDBe 2LNT · UniProt O95994

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