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Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, northeast structural genomics consortium target HR4411B

Analyse Solution NMR structure of homeobox domain (171-248) of human homeobox protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LK2
Type: protein
Length: 89 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Homeobox protein TGIF1
UniProt: Q15583
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 55% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Homeobox protein TGIF1	protein	89	55% helix, 0% strand	Q15583

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.30	0.76	12	empty

Compared structures

2LK2 · Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1… · the same entry in another collection · chain A against A, TM-score 1.00
Q15583 · AlphaFold monomer V2.0 prediction for homeobox protein TGIF1 (Q15583) · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15583
Elsewhere: RCSB PDB 2LK2 · PDBe 2LK2 · UniProt Q15583

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