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Solution structure of the oncogenic-potential MIEN1 protein

Analyse Solution structure of the oncogenic-potential MIEN1 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2LJK
Type
protein
Length
117 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein C17ORF37
UniProt
Q9BRT3
Pockets
3 · best druggability 0.59

Structure

solution nmr · 1 distinct chain · 18% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein C17ORF37protein11718% helix, 11% strandQ9BRT3

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1570.590.9012empty
21460.530.8025empty
3710.300.7317empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 2LJK · Solution structure of the oncogenic-potential MIEN1 protein · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9BRT3 · AlphaFold monomer V2.0 prediction for migration and invasion enhancer 1 (Q9BRT3) · a predicted model of the same protein · chain A against A, TM-score 0.69

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