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Structure of the duplex when (5'S)-8,5'-cyclo-2'-deoxyguanosine is placed opposite dt

Analyse Structure of the duplex when (5'S)-8,5'-cyclo-2'-deoxyguanosine is placed… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2LFX
Type
DNA
Length
24 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*TP*GP*CP*(2LF)P*TP*GP*TP*TP*TP*GP*T)-3'); DNA…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*GP*TP*GP*CP*(2LF)P*TP*GP*TP*TP*TP*GP*T)-3')dna12——
BDNA (5'-D(*AP*CP*AP*AP*AP*CP*AP*TP*GP*CP*AP*C)-3')dna12——

Interfaces

1 interface between chains.

  • A–B · 551 Ų buried · 42 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

  • 2LFX · Structure of the duplex when (5'S)-8,5'-cyclo-2'-deoxyguanosine is placed opposite dT · the same entry in another collection · chain A against A, TM-score 1.00

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