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Solution structure of the S. cerevisiae H/ACA rnp protein NHP2P-S82W mutant

Analyse Solution structure of the S. cerevisiae H/ACA rnp protein NHP2P-S82W mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LBW
Type: protein
Length: 121 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: H/ACA ribonucleoprotein complex subunit 2
UniProt: P32495
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 53% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	H/ACA ribonucleoprotein complex subunit 2	protein	121	53% helix, 12% strand	P32495

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.37	0.77	15	empty

Compared structures

2LBW · Solution structure of the S. cerevisiae H/ACA RNP protein Nhp2p-S82W mutant · the same entry in another collection · chain A against A, TM-score 1.00
P32495 · AlphaFold monomer V2.0 prediction for H/ACA ribonucleoprotein complex subunit NHP2… · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32495
Elsewhere: RCSB PDB 2LBW · PDBe 2LBW · UniProt P32495

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