Research workbench
Solution structure of PF1 SID1-MSIN3A PAH2 complex
Analyse Solution structure of PF1 SID1-MSIN3A PAH2 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2L9S
- Type
- protein
- Length
- 139 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phd finger protein 12; Paired amphipathic helix protein SIN3A
- UniProt
- Q96QT6, Q60520
- Pockets
- 1 · best druggability 0.30
Structure
solution nmr · 2 distinct chains · 51% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phd finger protein 12 | protein | 45 | 24% helix, 0% strand | Q96QT6 |
| B | Paired amphipathic helix protein SIN3A | protein | 94 | 64% helix, 0% strand | Q60520 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.30 | 0.74 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1051 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 2L9S · Solution structure of Pf1 SID1-mSin3A PAH2 Complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q60520 · AlphaFold monomer V2.0 prediction for paired amphipathic helix protein SIN3A (Q60520) · a predicted model of the same protein · chain B against A, TM-score 0.78
- Q96QT6 · AlphaFold monomer V2.0 prediction for phd finger protein 12 (Q96QT6) · a predicted model of the same protein · chain A against A, TM-score 0.36
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96QT6
- Every structure of UniProt Q60520
- Elsewhere: RCSB PDB 2L9S · PDBe 2L9S · UniProt Q96QT6 · UniProt Q60520
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