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Structure of a novel CBM3 lacking the calcium-binding site

Analyse Structure of a novel CBM3 lacking the calcium-binding site in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2L8A
Type: protein
Length: 149 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endoglucanase
EC: 3.2.1.4
UniProt: P10475
Pockets: 3 · best druggability 0.79

Structure

solution nmr · 1 distinct chain · 2% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endoglucanase (EC 3.2.1.4)	protein	149	2% helix, 36% strand	P10475

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	417	0.79	0.87	70	empty
2	56	0.34	0.78	16	empty
3	59	0.34	0.77	13	empty

Compared structures

2L8A · Structure of a novel CBM3 lacking the calcium-binding site · the same entry in another collection · chain A against A, TM-score 1.00
P10475 · AlphaFold monomer V2.0 prediction for endoglucanase (P10475) · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10475
Elsewhere: RCSB PDB 2L8A · PDBe 2L8A · UniProt P10475

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