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Solution structure of the third immunoglobulin-like domain of nectin-1

Analyse Solution structure of the third immunoglobulin-like domain of nectin-1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2L7J
Type
protein
Length
95 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Poliovirus receptor-related 1
UniProt
Q6P9M9
Pockets
1 · best druggability 0.61

Structure

solution nmr · 1 distinct chain · 3% helix, 48% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APoliovirus receptor-related 1protein953% helix, 48% strandQ6P9M9

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1890.610.8821empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 2L7J · Solution structure of the third Immunoglobulin-like domain of nectin-1 · the same entry in another collection · chain A against A, TM-score 1.00

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