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Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of gip with glutaminase L

Analyse Promiscuous binding at the crossroads of numerous cancer pathways: insight from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2L4S
Type: protein
Length: 124 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TAX1-binding protein 3
UniProt: O14907
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 10% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TAX1-binding protein 3	protein	124	10% helix, 25% strand	O14907

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.33	0.77	18	empty

Compared structures

2L4S · Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the… · the same entry in another collection · chain A against A, TM-score 1.00
O14907 · AlphaFold monomer V2.0 prediction for TAX1-binding protein 3 (O14907) · a predicted model of the same protein · chain A against A, TM-score 0.70

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14907
Elsewhere: RCSB PDB 2L4S · PDBe 2L4S · UniProt O14907

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