Research workbench

R29Q sticholysin II mutant

Analyse R29Q sticholysin II mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2L38
Type: protein
Length: 175 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sticholysin-2
UniProt: P07845
Pockets: 3 · best druggability 0.51

Structure

solution nmr · 1 distinct chain · 11% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sticholysin-2	protein	175	11% helix, 32% strand	P07845

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.51	0.81	22	empty
2	129	0.50	0.79	25	empty
3	77	0.48	0.83	25	empty

Compared structures

2L38 · R29Q Sticholysin II mutant · the same entry in another collection · chain A against A, TM-score 1.00
P07845 · AlphaFold monomer V2.0 prediction for delta-stichotoxin-SHE4B (P07845) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07845
Elsewhere: RCSB PDB 2L38 · PDBe 2L38 · UniProt P07845

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