Research workbench
NMR structure of the acid (activator interacting domain) of the human mediator MED25 protein
Analyse NMR structure of the acid (activator interacting domain) of the human mediator… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2L23
- Type
- protein
- Length
- 161 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mediator of RNA polymerase II transcription subunit 25
- UniProt
- B9TX31
- Pockets
- 2 · best druggability 0.58
Structure
solution nmr · 1 distinct chain · 23% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 25 | protein | 161 | 23% helix, 35% strand | B9TX31 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.58 | 0.84 | 20 | empty |
| 2 | 107 | 0.41 | 0.76 | 21 | empty |
Compared structures
- 2L23 · NMR structure of the ACID (ACtivator Interacting Domain) of the human mediator Med25… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B9TX31
- Elsewhere: RCSB PDB 2L23 · PDBe 2L23 · UniProt B9TX31
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