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Solution structure of a PREQ1 riboswitch (class I) aptamer bound to PREQ1

Analyse Solution structure of a PREQ1 riboswitch (class I) aptamer bound to PREQ1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2L1V
Type
RNA
Length
36 nucleotides
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
36-mer
Ligands
PRF
Pockets
2 · best druggability 0.40

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A36-merrna36——

Ligands and binding sites

  • PRF · 7-deaza-7-aminomethyl-guanine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1690.400.8014PRF
2570.230.718empty

Compared structures

  • 2L1V · Solution structure of a preQ1 riboswitch (Class I) aptamer bound to preQ1 · the same entry in another collection · chain A against A, TM-score 1.00

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