Research workbench
Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography
Analyse Structure of a conserved retroviral RNA packaging element by NMR spectroscopy… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2L1F
- Type
- RNA
- Length
- 131 nucleotides
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (65-mer); RNA (66-mer)
- Pockets
- 3 · best druggability 0.68
Structure
solution nmr · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA (65-mer) | rna | 65 | — | — |
| B | RNA (66-mer) | rna | 66 | — | — |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 900 | 0.68 | 0.75 | 42 | empty |
| 2 | 1140 | 0.67 | 0.74 | 63 | empty |
| 3 | 430 | 0.53 | 0.73 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 1142 Ų buried · 42 hydrogen bonds · nucleic-nucleic
Compared structures
- 2L1F · Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2L1F · PDBe 2L1F
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