Research workbench
Human regenerating gene type IV (reg IV) protein, P91S mutant
Analyse Human regenerating gene type IV (reg IV) protein, P91S mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KV3
- Type
- protein
- Length
- 131 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regenerating islet-derived protein 4
- UniProt
- Q9BYZ8
- Pockets
- 3 · best druggability 0.54
Structure
solution nmr · 1 distinct chain · 15% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regenerating islet-derived protein 4 | protein | 131 | 15% helix, 26% strand | Q9BYZ8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.54 | 0.81 | 25 | empty |
| 2 | 54 | 0.35 | 0.78 | 14 | empty |
| 3 | 53 | 0.28 | 0.75 | 16 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2KV3 · Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BYZ8 · AlphaFold monomer V2.0 prediction for regenerating islet-derived protein 4 (Q9BYZ8) · a predicted model of the same protein · chain A against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BYZ8
- Elsewhere: RCSB PDB 2KV3 · PDBe 2KV3 · UniProt Q9BYZ8
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