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Solution structure of a divergent BCL-2 protein

Analyse Solution structure of a divergent BCL-2 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KUA
Type: protein
Length: 170 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BCL-2-like protein 10
UniProt: Q9Z0F3
Pockets: 3 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 59% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BCL-2-like protein 10	protein	170	59% helix, 0% strand	Q9Z0F3

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	185	0.49	0.76	36	empty
2	65	0.38	0.79	18	empty
3	51	0.29	0.76	15	empty

Compared structures

2KUA · Solution structure of a divergent Bcl-2 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9Z0F3 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 10 (Q9Z0F3) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z0F3
Elsewhere: RCSB PDB 2KUA · PDBe 2KUA · UniProt Q9Z0F3

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