Research workbench
Solution structure of the al-09 H87Y immunoglobulin light chain variable domain
Analyse Solution structure of the al-09 H87Y immunoglobulin light chain variable domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KQN
- Type
- protein
- Length
- 216 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ig kappa chain V-I region au
- Pockets
- 3 · best druggability 0.32
Structure
solution nmr · 1 distinct chain · 3% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ig kappa chain V-I region au | protein | 108 | 3% helix, 46% strand | — |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 75 | 0.32 | 0.74 | 14 | empty |
| 2 | 82 | 0.32 | 0.74 | 17 | empty |
| 3 | 70 | 0.29 | 0.74 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 724 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2KQN · Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2KQN · PDBe 2KQN
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