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Structure of 2'F-ANA/RNA hybrid duplex

Analyse Structure of 2'F-ANA/RNA hybrid duplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2KP4
Type
DNA + RNA
Length
20 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*(GFL)P*(CFL)P*(TAF)P*(A5L)P*(TAF)P*(A5L)P*(A5L) P*(TAF)P*(GFL)P*(GFL))-3')…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*(GFL)P*(CFL)P*(TAF)P*(A5L)P*(TAF)P*(A5L)P*(A5L) P*(TAF)P*(GFL)P*(GFL))-3')dna10——
BRNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3')rna10——

Interfaces

1 interface between chains.

  • A–B · 474 Ų buried · 42 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 10 modified (nucleotide modification).

Compared structures

  • 2KP4 · Structure of 2'F-ANA/RNA hybrid duplex · the same entry in another collection · chain A against A, TM-score 1.00

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