Research workbench
MESD(12-155), the core structural domain of mesd that is essential for proper folding of LRP5/6
Analyse MESD(12-155), the core structural domain of mesd that is essential for proper… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KMI
- Type
- protein
- Length
- 145 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mesoderm development candidate 2
- UniProt
- Q9ERE7
- Pockets
- 3 · best druggability 0.55
Structure
solution nmr · 1 distinct chain · 32% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mesoderm development candidate 2 | protein | 145 | 32% helix, 19% strand | Q9ERE7 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.55 | 0.88 | 19 | empty |
| 2 | 99 | 0.50 | 0.82 | 24 | empty |
| 3 | 74 | 0.33 | 0.74 | 14 | empty |
Compared structures
- 2KMI · MESD(12-155), The Core Structural Domain of MESD that Is Essential for Proper Folding of… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9ERE7 · AlphaFold monomer V2.0 prediction for lrp chaperone mesd (Q9ERE7) · a predicted model of the same protein · chain A against A, TM-score 0.25
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ERE7
- Elsewhere: RCSB PDB 2KMI · PDBe 2KMI · UniProt Q9ERE7
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