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Solution NMR structure of the EGF-like 1 domain of human fibulin-4. northeast structural genomics target HR6275

Analyse Solution NMR structure of the EGF-like 1 domain of human fibulin-4. northeast… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KL7
Type: protein
Length: 71 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibulin-4
UniProt: O95967
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 0% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibulin-4	protein	71	0% helix, 21% strand	O95967

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.33	0.75	19	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2KL7 · Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural… · the same entry in another collection · chain A against A, TM-score 1.00
O95967 · AlphaFold monomer V2.0 prediction for EGF-containing fibulin-like extracellular matrix… · a predicted model of the same protein · chain A against A, TM-score 0.30

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95967
Elsewhere: RCSB PDB 2KL7 · PDBe 2KL7 · UniProt O95967

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