Research workbench
The solution structure of RPP29-RPP21 complex from pyrococcus furiosus
Analyse The solution structure of RPP29-RPP21 complex from pyrococcus furiosus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KI7
- Type
- protein
- Length
- 208 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribonuclease P protein component 1; Ribonuclease P protein component 4
- EC
- 3.1.26.5
- UniProt
- Q8U007, Q8U0H6
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.59
Structure
solution nmr · 2 distinct chains · 27% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribonuclease P protein component 1 (EC 3.1.26.5) | protein | 111 | 13% helix, 33% strand | Q8U007 |
| B | Ribonuclease P protein component 4 (EC 3.1.26.5) | protein | 97 | 43% helix, 22% strand | Q8U0H6 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.59 | 0.86 | 22 | empty |
| 2 | 56 | 0.56 | 0.89 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1265 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 2KI7 · The solution structure of RPP29-RPP21 complex from Pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00
- Q8U007 · AlphaFold monomer V2.0 prediction for ribonuclease P protein component 1 (Q8U007) · a predicted model of the same protein · chain A against A, TM-score 0.81
- Q8U0H6 · AlphaFold monomer V2.0 prediction for ribonuclease P protein component 4 (Q8U0H6) · a predicted model of the same protein · chain B against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8U007
- Every structure of UniProt Q8U0H6
- Elsewhere: RCSB PDB 2KI7 · PDBe 2KI7 · UniProt Q8U007 · UniProt Q8U0H6
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