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Solution structure of rcl

Analyse Solution structure of rcl in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KHZ
Type: protein
Length: 326 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-myc-responsive protein rcl
UniProt: O35820
Pockets: 3 · best druggability 0.66

Structure

solution nmr · 1 distinct chain · 37% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	C-myc-responsive protein rcl	protein	163	37% helix, 13% strand	O35820

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	189	0.66	0.85	38	empty
2	193	0.66	0.85	41	empty
3	54	0.26	0.74	12	empty

Interfaces

1 interface between chains.

A–B · 1434 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

2KHZ · Solution Structure of RCL · the same entry in another collection · chain A against A, TM-score 1.00
O35820 · AlphaFold monomer V2.0 prediction for 2'-deoxynucleoside 5'-phosphate N-hydrolase 1… · a predicted model of the same protein · chain B against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O35820
Elsewhere: RCSB PDB 2KHZ · PDBe 2KHZ · UniProt O35820

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