Research workbench
Structure and features of the complex formed by the tuberculosis virulence factors RV0287 and RV0288
Analyse Structure and features of the complex formed by the tuberculosis virulence… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KG7
- Type
- protein
- Length
- 194 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein esxg (pe family protein); Esat-6-like protein esxh
- UniProt
- O53692, P0A568
- Pockets
- 1 · best druggability 0.56
Structure
solution nmr · 2 distinct chains · 56% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein esxg (pe family protein) | protein | 97 | 56% helix, 0% strand | O53692 |
| B | Esat-6-like protein esxh | protein | 97 | 56% helix, 0% strand | P0A568 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 277 | 0.56 | 0.77 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 1310 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 2KG7 · Structure and features of the complex formed by the tuberculosis virulence factors Rv0287… · the same entry in another collection · chain A against A, TM-score 1.00
- O53692 · AlphaFold monomer V2.0 prediction for esat-6-like protein esxg (O53692) · a predicted model of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O53692
- Every structure of UniProt P0A568
- Elsewhere: RCSB PDB 2KG7 · PDBe 2KG7 · UniProt O53692 · UniProt P0A568
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.